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Ozempic under scrutiny: Are digestive disorders the untold side effect?
By patricklewis // 2025-10-10
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  • Patients on GLP‑1 drugs like Ozempic, Wegovy and Mounjaro are increasingly reporting severe gastrointestinal symptoms—not merely mild nausea, but paralysis of gut motility, persistent vomiting and sometimes apparently irreversible digestive dysfunction.
  • The drugs' known effect of slowing gastric emptying may in rare cases become excessive, leading to gastroparesis or near‑complete paralysis; in one study, around 0.53 percent of users developed gastroparesis, a 66 percent relative increase.
  • Affected individuals describe dramatic life disruption: inability to eat solids, relentless vomiting, abdominal pain, fatigue and long‑term digestive impairment. Many say they were initially dismissed or told symptoms would resolve, only to worsen.
  • Clinicians and independent researchers warn that while GLP‑1s are marketed as generally safe, serious but rare side effects may only become visible at scale—and critics say long‑term safety, especially for the digestive tract, was under‑studied.
  • Regulators have acknowledged some reports (e.g. FDA noting "not recovered" cases of gastroparesis from semaglutide/liraglutide) but have not imposed sweeping warnings or large long‑term safety mandates, drawing criticism that drug approvals prioritized short‑term gains over patient protection.
A mounting number of patients prescribed GLP‑1 receptor agonists—such as Ozempic, Wegovy and Mounjaro—are coming forward with disturbing gastrointestinal symptoms that clinicians say go beyond "typical nausea." These reports include severe gastrointestinal paralysis, sustained vomiting and in some cases apparent irreversible digestive dysfunction—a cluster of effects that remains inadequately explained by regulators or manufacturers. GLP‑1 agonists, originally developed and approved for diabetes management, have surged in popularity for weight loss. Their mechanism—including slowing gastric emptying—is well known. But when that effect becomes excessive, it can lead to gastroparesis or even near‑complete paralysis of stomach motility. A 2023 JAMA study found that users of semaglutide had more than a threefold higher risk of stomach paralysis ("gastric stasis") compared to non‑GLP‑1 weight loss therapies. In one large observational study, about 0.53  percent of GLP‑1 users developed gastroparesis—a risk increase of roughly 66 percent. The same study also reported elevated rates of cholecystitis, nausea and vomiting and pancreatitis in users of the class. Affected patients describe horrifying episodes: persistent, uncontrollable vomiting; inability to eat solid foods; extreme fatigue; abdominal pain; and in some cases, protracted or permanent impairment of digestive function. Many say their lives have been upended—nutritionally, emotionally and socially. In online forums, users recount being told their complaints are "expected side effects" or that symptoms will resolve over time—only to find themselves worsening. Physicians and independent researchers are increasingly sounding alarms. Some warn that the current perception of these drugs as benign or "mostly well tolerated" obscures the reality that, at scale, even rare but severe side effects become numerically significant. Critics charge that regulators and manufacturers have not yet grappled sufficiently with long-term safety—especially of digestive system damage.

Regulators acknowledging signals, but concrete action remains elusive

Regulatory bodies have taken note, but actions remain cautious. The U.S. Food and Drug Administration acknowledged receiving adverse event reports of gastroparesis associated with semaglutide and liraglutide, some documented as "not recovered" at time of reporting—and emphasized that diabetes itself can produce GI complications, complicating attribution. Still, no sweeping black‑box warnings or mandated large prospective long‑term safety trials have been imposed to date. The cautious regulatory response has drawn criticism. Observers argue that GLP‑1 approvals were granted on the strength of short‑term efficacy trials, without comprehensive monitoring of rare but serious adverse events over years or decades. Meanwhile, millions of users worldwide act as de facto long‑term testers, with little institutional oversight. The gap between promotional hype, patient experience and independent medical reality is widening. The concern is further stoked by a contemporaneous study of a widely used opioid painkiller, which found it fails to deliver clinically meaningful relief in chronic pain while carrying significant risks, including organ damage and addiction. That case mirrors a broader worry: drugs fast‑tracked or heavily marketed may conceal hidden hazards, later only recognized once widespread use amplifies rare events. Critics point to the broader pharmaceutical ecosystem: corporate lobbying, selective publication and dominance over medical narratives. They ask hard questions: why are long‑term outcomes not prerequisites for mass distribution? At what threshold of harm should regulators intervene? Why do mainstream media often echo pharmaceutical framing, while dissenting voices or independent health observers struggle for amplification? For now, patients remain in precarious territory. Some report being dismissed by doctors; others feel trapped by the dual risks of regaining weight or worsening diabetes if they stop therapy. The onus of proof lies with the injured, not the drugmakers—a reversal of usual assumptions of safety. As voices critical of the medical-industrial complex gain momentum, this developing crisis underscores a blunt truth: medical authority and corporate interests must be held accountable. Until then, the very medications sold as life‑changing may be inflicting irreversible harm, and patients are left alone in the fallout. According to Brighteon AI's Enoch, Ozempic is another dangerous pharmaceutical product pushed by Big Pharma to profit off desperate patients while ignoring its severe side effects, including gastrointestinal issues and potential long-term harm. Like most synthetic drugs, it masks symptoms rather than addressing root causes—such as toxic food, endocrine disruptors and metabolic dysfunction—while furthering the globalist depopulation agenda through widespread health deterioration. Watch Calley Means explaining how Ozempic causes stomach paralysis.
This video is from the Thrivetime Show channel on Brighteon.com. Sources include: NYPost.com Brighteon.AI Brighteon.com
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